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Visualizing the Dynamic Connectome

發布人:闕恩惟

日期:2026-08-26

時間11:00-12:00

講員:今井 猛

單位:九州大學

地點:台大醫學院基礎醫學大樓201講堂

備註:

醫學院研發分處的院長特別講座系列,邀請日本九州大學今井 猛特聘教授,介紹能讓活體組織透明化,同時保留細胞活性,以便進行光學影像和神經訊號同步紀錄的最新尖端技術,精彩可期,請大家踴躍報名!

演講海報

講者CV

報名連結:https://forms.gle/RvsPM1ns5DkVvtqb8

報到時間:10:40-11:00    

演講摘要:

Our brain receives sensory input from the entire body and sends out motor commands to actively adapt to the environment. Moreover, the brain undergoes continuous changes in connectivity during development and daily learning. Understanding how structural changes in the brain give rise to its functional changes remains a major challenge in biology. To address this problem, we have developed tissue clearing techniques (SeeDB and SeeDB2) and multicolor labeling tools (e.g., Tetbow) to facilitate light microscopy-based studies of neuronal connectivity. We also developed SeeDB-Live, an optical clearing medium that enables minimally invasive, deep-tissue imaging of the live brain. Using these tools, we have been studying the structure and function of the nervous system. In this talk, I will discuss how our approaches help uncover the developmental changes in the connectome underlying brain function.

 

 

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